Look for the Isabelline Shrike in open, arid to semi-arid habitats such as steppes, scrublands, deserts with scattered bushes, and sometimes agricultural areas. During migration, they can appear in a wider range of open landscapes. They are often spotted perched prominently on wires, fences, the tops of bushes, or other elevated vantage points.

Spotting the Isabelline Shrike involves looking for its upright posture and characteristic 'shrike' behavior of perching high to scan for prey. Its calls include harsh, rattling alarm notes and churring sounds, though it can also produce softer, more melodious phrases in its song. Observe for its predatory dives and the unique behavior of impaling prey on thorns or barbed wire.

This species is a summer breeder in Central Asia, undertaking long-distance migrations to its wintering grounds in East Africa, the Arabian Peninsula, and India. The best times to observe them in transit countries are during the spring (April-May) and autumn (August-October) migration periods. In breeding and wintering grounds, they are active during daylight hours.